Article
Human glial fibrillary acidic protein: complementary DNA cloning, chromosome localization, and messenger RNA expression in human glioma cell lines of various phenotypes.
Cancer research - 1 Mar 1991
Bongcam-Rudloff E, Nistér M, Betsholtz C, Wang J L, Stenman G, Huebner K, Croce C M, Westermark B
Abstract excerpt
Glial fibrillary acidic protein (GFAP) is a constituent of intermediate filaments of glial cells of the astrocyte lineage. We cloned a human GFAP complementary DNA, deduced the amino acid sequence, and established the chromosomal location (17q21) of the GFAP gene by Southern blot hybridization of somatic cell hybrids and by in situ hybridization. The authenticity of the complementary DNA was proven by expressing...
Topics
- Chromosome Mapping
- Cloning, Molecular
- DNA
- Fibronectins
- Glial Fibrillary Acidic Protein
- Glioma
- Humans
- Phenotype
- RNA, Messenger
- Receptors, Cell Surface