Article
Cell-specific expression of the mouse glial fibrillary acidic protein gene: identification of the cis- and trans-acting promoter elements for astrocyte-specific expression.
Journal of neurochemistry - 1 Oct 1990
Miura M, Tamura T, Mikoshiba K
Abstract excerpt
We have determined the whole promoter sequence and the transcriptional startpoint of the mouse glial fibrillary acidic protein (GFAP) gene and characterized the promoter function. We found that the cis elements for astrocyte specific expression are located within 256 bp from the transcription sta...
Topics
- Animals
- Astrocytes
- Base Sequence
- Brain
- Cell Line
- Cloning, Molecular
- DNA
- Gene Expression
- Genes
- Genomic Library
- Glial Fibrillary Acidic Protein
- Mice
- Mice, Inbred ICR
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Organ Specificity
- Promoter Regions, Genetic