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Article

Astrocyte heterogeneity revealed by expression of a GFAP-LacZ transgene.

Glia - 1 May 2006

Lee Youngjin, Su Mu, Messing Albee, Brenner Michael

Abstract excerpt

Glial fibrillary acidic protein (GFAP) is an intermediate filament protein present primarily in astrocytes. The gene is first expressed as astrocytes mature, and in the adult is strongly upregulated in response to CNS damage. Thus, in addition to its astrocyte specificity, transcriptional regulation of the GFAP gene is of interest as a reporter of CNS signaling during development and injury. Several laboratories...

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Source

Identifiers

PMID: 16482522
DOI: 10.1002/glia.20320

Genes

GFAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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