Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GFAP promoter elements required for region-specific and astrocyte-specific expression.

Glia - 1 Apr 2008

Lee Youngjin, Messing Albee, Su Mu, Brenner Michael

Abstract excerpt

Glial fibrillary acidic protein (GFAP) is the major intermediate filament protein in astrocytes, one of the most abundant cell types in the vertebrate central nervous system (CNS). Transcriptional regulation of GFAP is of interest because of its astrocyte-specificity and its upregulation during development and CNS injury. A 2.2 kb human GFAP promoter, gfa2, has been found to express in astrocytes throughout the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Motifs
Share to Animals, Newborn
Share to Astrocytes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to beta-Galactosidase

Share to Electrophoretic Mobility Shift Assay

Share to Glial Fibrillary Acidic Protein

Share to Glioma

Share to Phosphopyruvate Hydratase

Source

Identifiers

PMID: 18240313
DOI: 10.1002/glia.20622

Genes

GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GFAP promoter elements required for region-specific and astrocyte-specific expression.PMID 18240313Read ↗

Astrocyte heterogeneity revealed by expression of a GFAP-LacZ transgene.Semantic proximity Read ↗

Transgenic analysis of GFAP promoter elements.Semantic proximity Read ↗

Glial fibrillary acidic protein gene promoter is differently modulated by transforming growth factor‐beta 1 in astrocytes from distinct brain regionsSemantic proximity Read ↗

Cell-specific expression of the mouse glial fibrillary acidic protein gene: identification of the cis- and trans-acting promoter elements for astrocyte-specific expression.Semantic proximity Read ↗

New GFAP splice isoform (GFAPµ) differentially expressed in glioma translates into 21 kDa N‐terminal GFAP proteinSemantic proximity Read ↗

GFAP Alternative Splicing and the Relevance for Disease – A Focus on Diffuse GliomasSemantic proximity Read ↗

Epigenetic regulation of glial fibrillary acidic protein by DNA methylation in human malignant gliomasSemantic proximity Read ↗

New GFAP splice isoform (GFAPμ) differentially expressed in glioma translates into 21 kDa N-terminal GFAP proteinSemantic proximity Read ↗

Transgenic techniques for cell ablation or molecular deletion to investigate functions of astrocytes and other GFAP-expressing cell types.Semantic proximity Read ↗

A toolbox of astrocyte-specific, serotype-independent adeno-associated viral vectors using microRNA targeting sequencesSemantic proximity Read ↗

The Exon Junction Complex Factor RBM8A in Glial Fibrillary Acid Protein-Expressing Astrocytes Modulates Locomotion BehaviorsSemantic proximity Read ↗

GFAP promoter driven transgenic expression of PDGFB in the mouse brain leads to glioblastoma in a <i>Trp53 null</i> backgroundSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.