Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular screening of the 11beta-HSD1 gene in men characterized by the metabolic syndrome.

Obesity research - 1 Oct 2004

Robitaille Julie, Brouillette Charles, Houde Alain, Després Jean-Pierre, Tchernof André, Vohl Marie-Claude

Abstract excerpt

Adipose tissue type 1 11beta-hydroxysteroid dehydrogenase (11beta-HSD1), which generates hormonally active cortisol from inactive cortisone, has been shown to play a central role in adipocyte differentiation and abdominal obesity-related metabolic complications. The objective was to investigate whether genetic variations in the human 11beta-HSD1 gene are associated with the metabolic syndrome among...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Exons
Share to Gene Frequency
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mass Screening

Share to Metabolic Syndrome

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 15536220
DOI: 10.1038/oby.2004.196

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular screening of the 11beta-HSD1 gene in men characterized by the metabolic syndrome.PMID 15536220Read ↗

Association study of 11beta-hydroxysteroid dehydrogenase type 1 gene polymorphisms and metabolic syndrome in urban Japanese cohort.Semantic proximity Read ↗

Functional effects of polymorphisms in the human gene encoding 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1): a sequence variant at the translation start of 11 beta-HSD1 alters enzyme levels.Semantic proximity Read ↗

Association between a 11β-hydroxysteroid dehydrogenase type 1 gene polymorphism and metabolic syndrome in a South Indian population.Semantic proximity Read ↗

Association studies between microsatellite markers within the gene encoding human 11beta-hydroxysteroid dehydrogenase type 1 and body mass index, waist to hip ratio, and glucocorticoid metabolism.Semantic proximity Read ↗

Association between 11beta-hydroxysteroid dehydrogenase type 1 gene polymorphisms and metabolic syndrome in Bosnian population.Semantic proximity Read ↗

11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response.Semantic proximity Read ↗

Regulatory effect of common promoter polymorphisms on the expression of the 11beta-hydroxysteroid dehydrogenase type 1 gene.Semantic proximity Read ↗

Genetic variation in 11beta-hydroxysteroid dehydrogenase type 1 predicts adrenal hyperandrogenism among lean women with polycystic ovary syndrome.Semantic proximity Read ↗

11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects.Semantic proximity Read ↗

Polymorphic variants of the HSD11B1 gene may be involved in adverse metabolic effects of glucocorticoid replacement therapy in Addison's disease.Semantic proximity Read ↗

Lack of mutations of type 1 11beta-hydroxysteroid dehydrogenase gene in patients with abdominal obesity.Semantic proximity Read ↗

Impact of HSD11B1 polymorphisms on BMI and components of the metabolic syndrome in patients receiving psychotropic treatments.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.