Article
PPARgamma Pro12Ala polymorphism in HIV-1-infected patients with HAART-related lipodystrophy.
Current HIV research - 1 Sept 2009
Saumoy Maria, Veloso Sergi, Alonso-Villaverde Carlos, Domingo Pere, Chacón Matilde R, Miranda Merce, Aragonès Gerard, Gutiérrez Maria Mar, Viladés Consuelo, Peraire Joaquim, Sirvent Joan-Josep, López-Dupla Miguel, Aguilar Carmen, Richart Cristóbal, Vidal Francesc
Abstract excerpt
Peroxisome proliferator-activated receptor gamma (PPARgamma) is involved in obesity and in some components of the metabolic syndrome in unselected population. To determine whether PPARgamma genetic variants are associated with the risk of developing lipodystrophy and its associated metabolic disturbances in HIV-1-infected patients treated with HAART and to assess PPARgamma mRNA expression in subcutaneous adipose...
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