Article
SNPs in the APM1 gene promoter are associated with adiponectin levels in HIV-infected individuals receiving HAART.
Journal of acquired immune deficiency syndromes (1999) - 1 Nov 2010
Trinca Juciane R, Sprinz Eduardo, Lazzaretti Rosmeri K, Hutz Mara H, Kuhmmer Regina, de Almeida Silvana, Tibola Analise, Meirelles Gustavo B, Arena-de-Souza Roberto C, Mattevi Vanessa S
Abstract excerpt
OBJECTIVE: This study aimed to investigate the association between 4 polymorphisms in the leptin, leptin receptor, and adiponectin (APM1) genes and the occurrence of lipodystrophy and dyslipidemia in HIV-infected patients receiving highly active antiretroviral therapy (HAART). MATERIALS AND METHODS: Genotypes of 410 HIV-infected patients on HAART were investigated. Anthropometric (weight, height, waist...
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