Article
Effect of the Pro12Ala variant of the human peroxisome proliferator-activated receptor gamma 2 gene on adiposity, fat distribution, and insulin sensitivity in Japanese men.
Biochemical and biophysical research communications - 9 Oct 1998
Mori Y, Kim-Motoyama H, Katakura T, Yasuda K, Kadowaki H, Beamer B A, Shuldiner A R, Akanuma Y, Yazaki Y, Kadowaki T
Abstract excerpt
To examine the role of the Pro12Ala variant of the human PPARgamma2 gene on adiposity and insulin resistance, we studied the effect of the variant on fat distribution assessed by CT scan, plasma glucose, and insulin levels during a 75g oral glucose load in 215 non-diabetic Japanese men. The allel...
Topics
- Adipose Tissue
- Adult
- Aged
- Alanine
- Amino Acid Substitution
- Blood Pressure
- Body Mass Index
- Fats
- Genetic Variation
- Humans
- Insulin Resistance
- Japan
- Lipids
- Male
- Middle Aged