PPARγ2 Pro12Ala polymorphism was associated with favorable cardiometabolic risk profile in HIV/HCV coinfected patients: a cross-sectional study.

doi:10.1186/s12967-014-0235-9

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Article

PPARγ2 Pro12Ala polymorphism was associated with favorable cardiometabolic risk profile in HIV/HCV coinfected patients: a cross-sectional study.

Journal of translational medicine - 27 Aug 2014

García-Broncano Pilar, Berenguer Juan, Fernández-Rodríguez Amanda, Pineda-Tenor Daniel, Jiménez-Sousa María Ángeles, García-Alvarez Mónica, Miralles Pilar, Aldámiz-Echevarria Teresa, López Juan Carlos, Micheloud Dariela, Resino Salvador

Abstract excerpt

BACKGROUND: Peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) rs1801282 (Pro12Ala) polymorphism has been associated with lower risk of metabolic disturbance and atherosclerosis. The aim of this study was to analyze the association between the Pro12Ala polymorphism and cardiometabolic risk factors in human immunodeficiency virus (HIV)/Hepatitis C virus (HCV)-coinfected patients. METHODS: We carried...

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PMID: 25159899
DOI: 10.1186/s12967-014-0235-9
PMCID: PMC4282155

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