Article
High loading dose of clopidogrel is unable to satisfactorily inhibit platelet reactivity in patients with glycoprotein IIIA gene polymorphism: a genetic substudy of PRAGUE-8 trial.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jun 2009
Motovska Zuzana, Widimsky Petr, Kvasnicka Jan, Petr Robert, Bilkova Dana, Hajkova Jaroslava, Marinov Iuri, Simek Stanislav, Kala Petr
Abstract excerpt
The study aimed to assess the impact of nine polymorphisms of genes encoding platelet receptors, enzymes, and hemostatic factors on clopidogrel efficacy to inhibit platelet reactivity in patients with stable coronary artery disease undergoing elective coronary angiography either with or without ad hoc percutaneous coronary intervention. The study was performed as a genetic substudy of the PRAGUE-8 trial....
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