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Article

Clinical, genetic and confounding factors determine the dynamics of the in vitro response/non response to clopidogrel

1 Jan 2011

Abstract excerpt

Platelet inhibition by clopidogrel varies from one individual to the next. Further, in vitro high on-treatment residual adenosine-diphosphate inducible platelet reactivity (HRPR) is associated with an increased risk for major adverse cardiovascular events after percutaneous coronary intervention (PCI) with stent implantation. Recent studies identified numerous influencing factors for the antiplatelet effect of...

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PMID: 21614418
DOI: 10.1160/th11-03-0137

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