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Article

Apurinic/apyrimidinic endonuclease (APE1) gene polymorphisms and lung cancer risk in relation to tobacco smoking.

Anticancer research - 1 Jun 2009

Agaçhan Bedia, Küçükhüseyin Ozlem, Aksoy Pinar, Turna Akif, Yaylim Ilhan, Görmüs Uzay, Ergen Arzu, Zeybek Umit, Dalan Burak, Isbir Turgay

Abstract excerpt

BACKGROUND: Polymorphisms altering DNA repair capacity may lead to synergistic effects with tobacco carcinogen-induced lung cancer risk. Based on this hypothesis, the relationship between APE1 polymorphism, smoking and the risk of lung cancer was explored. MATERIALS AND METHODS: The distribution of the APE1 Asp148Glu polymorphisms in 98 lung cancer patients and 67 healthy individuals were compared using PCR-RFLP...

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PMID: 19528510

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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