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Article

Plasma selenium, manganese superoxide dismutase, and intermediate- or high-risk prostate cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Aug 2009

Chan June M, Oh William K, Xie Wanling, Regan Meredith M, Stampfer Meir J, King Irena B, Abe Miyako, Kantoff Philip W

Abstract excerpt

PURPOSE: In vitro, in vivo, and epidemiologic studies support a role for selenium in reducing the risk of prostate cancer. Our group previously demonstrated a strong interaction between plasma selenium and the manganese superoxide dismutase (SOD2) gene and incident prostate cancer risk. We now hypothesized that SOD2 modifies the association between selenium level and risk of aggressive prostate cancer at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19528373
DOI: 10.1200/JCO.2008.18.8938
PMCID: PMC2720077

Genes

SOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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