Article
Association of genetic variations of selenoprotein genes, plasma selenium levels, and prostate cancer aggressiveness at diagnosis.
The Prostate - 1 May 2016
Xie Wanling, Yang Ming, Chan June, Sun Tong, Mucci Lorelei A, Penney Kathryn L, Lee Gwo-Shu Mary, Kantoff Philip W
Abstract excerpt
BACKGROUND: Genetic variations in some of the selenoprotein genes, alone or together with an individual's selenium status, may influence risk or progression of prostate cancer. We investigated the impact of genetic variants of selenoproteins on plasma selenium levels and cancer aggressiveness at diagnosis in men with localized prostate cancer (PCa). METHODS: The study cohort comprised 722 patients seen at...
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