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Article

The common G-866A polymorphism of the UCP2 gene and survival in diabetic patients following myocardial infarction.

Cardiovascular diabetology - 15 Jun 2009

Palmer Barry R, Devereaux Courtney L, Dhamrait Sukhbir S, Mocatta Tessa J, Pilbrow Anna P, Frampton Chris M, Skelton Lorraine, Yandle Tim G, Winterbourn Christine C, Richards A Mark, Montgomery Hugh E, Cameron Vicky A

Abstract excerpt

BACKGROUND: A variant in the promoter of the human uncoupling protein 2 (UCP2) gene, the G-866A polymorphism, has been associated with future risk of coronary heart disease events, in those devoid of traditional risk factors and in those suffering from diabetes. We thus examined the impact of the G-866A polymorphism on 5-year survival in a cohort of 901 post-myocardial infarction patients, and the impact of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19527523
DOI: 10.1186/1475-2840-8-31
PMCID: PMC2702310

Genes

UCP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The common G-866A polymorphism of the UCP2 gene and survival in diabetic patients following myocardial infarction.PMID 19527523Read ↗

The common -866G>A variant in the promoter of UCP2 is associated with decreased risk of coronary artery disease in type 2 diabetic men.Semantic proximity Read ↗

Cardiovascular risk in healthy men and markers of oxidative stress in diabetic men are associated with common variation in the gene for uncoupling protein 2.Semantic proximity Read ↗

Interaction between the UCP2 -866 G>A polymorphism, diabetes, and beta-blocker use among patients with acute coronary syndromes.Semantic proximity Read ↗

Uncoupling protein 2 -866G/A and uncoupling protein 3 -55C/T polymorphisms in young South African Indian coronary artery disease patients.Semantic proximity Read ↗

Functional polymorphisms of UCP2 and UCP3 are associated with a reduced prevalence of diabetic neuropathy in patients with type 1 diabetes.Semantic proximity Read ↗

Interaction between the uncoupling protein 2 -866G>A gene variant and cigarette smoking to increase oxidative stress in subjects with diabetes.Semantic proximity Read ↗

Uncoupling protein 2 G(-866)A polymorphism: a new gene polymorphism associated with C-reactive protein in type 2 diabetic patients.Semantic proximity Read ↗

Mitochondrial uncoupling protein 2 (UCP2) gene polymorphism -866 G/A in the promoter region is associated with Type 2 Diabetes Mellitus among Kashmiri population of Northern IndiaSemantic proximity Read ↗

Associations of the UCP2 gene locus with asymptomatic carotid atherosclerosis in middle-aged women.Semantic proximity Read ↗

Mitochondrial uncoupling protein 2 (UCP2) gene polymorphism - 866 G/A in the promoter region is associated with type 2 diabetes mellitus among Kashmiri population of Northern India.Semantic proximity Read ↗

Association between UCP2 A55V polymorphism and risk of cardiovascular events in patients with multi-vessel coronary arterial disease.Semantic proximity Read ↗

Uncoupling protein 2 promoter polymorphism -866G/A affects peripheral nerve dysfunction in Japanese type 2 diabetic patients.Semantic proximity Read ↗

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