Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional polymorphisms of UCP2 and UCP3 are associated with a reduced prevalence of diabetic neuropathy in patients with type 1 diabetes.

Diabetes care - 1 Jan 2006

Rudofsky Gottfried, Schroedter Antonia, Schlotterer Andreas, Voron'ko Olga E, Schlimme Martin, Tafel Joerg, Isermann Berend H, Humpert Per M, Morcos Michael, Bierhaus Angelika, Nawroth Peter P, Hamann Andreas

Abstract excerpt

OBJECTIVE: We studied the association between polymorphisms in the UCP genes and diabetes complications in patients with type 1 diabetes. RESEARCH DESIGN AND METHODS: We analyzed 227 patients with type 1 diabetes using PCR and subsequent cleavage by restriction endonucleases for the promoter variants A-3826G in the UCP1 gene, G-866A in the UCP2 gene, and C-55T in the UCP3 gene. RESULTS: No effect of the A-3826G...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 1
Share to Diabetic Neuropathies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Carrier Screening

Share to Ion Channels

Share to Membrane Transport Proteins

Share to Mitochondrial Proteins

Share to Uncoupling Protein 2

Share to Uncoupling Protein 3

Source

Identifiers

PMID: 16373902
DOI: 10.2337/diacare.29.01.06.dc05-0757

Genes

UCP2
UCP3
UCP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional polymorphisms of UCP2 and UCP3 are associated with a reduced prevalence of diabetic neuropathy in patients with type 1 diabetes.PMID 16373902Read ↗

Associations between UCP1 -3826A/G, UCP2 -866G/A, Ala55Val and Ins/Del, and UCP3 -55C/T polymorphisms and susceptibility to type 2 diabetes mellitus: case-control study and meta-analysis.Semantic proximity Read ↗

Uncoupling protein 2 promoter polymorphism -866G/A affects peripheral nerve dysfunction in Japanese type 2 diabetic patients.Semantic proximity Read ↗

Associations between polymorphisms in the mitochondrial uncoupling proteins (UCPs) with T2DM.Semantic proximity Read ↗

The polymorphisms of UCP2 and UCP3 genes associated with fat metabolism, obesity and diabetes.Semantic proximity Read ↗

Uncoupling protein 2 and 3 gene polymorphisms and their association with type 2 diabetes in asian indians.Semantic proximity Read ↗

Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion.Semantic proximity Read ↗

Ethnicity Differences in the Association of UCP1-3826A/G, UCP2-866G/A and Ala55Val, and UCP3-55C/T Polymorphisms with Type 2 Diabetes Mellitus Susceptibility: An Updated Meta-Analysis.Semantic proximity Read ↗

Polymorphisms of the UCP2 Gene Are Associated with Glomerular Filtration Rate in Type 2 Diabetic Patients and with Decreased UCP2 Gene Expression in Human KidneySemantic proximity Read ↗

Variation in the UCP2-UCP3 gene cluster predicts the development of type 2 diabetes in healthy middle-aged men.Semantic proximity Read ↗

Association of uncoupling protein-2 -866G/A and Ala55Val polymorphisms with susceptibility to type 2 diabetes mellitus: A meta-analysis of case-control studies.Semantic proximity Read ↗

Analysis of association between common variants of uncoupling proteins genes and diabetic retinopathy in a Chinese population.Semantic proximity Read ↗

A polymorphism in the 5' untranslated region and a Met229-->Leu variant in exon 5 of the human UCP1 gene are associated with susceptibility to type II diabetes mellitus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.