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Article

Uncoupling protein 2 promoter polymorphism -866G/A affects peripheral nerve dysfunction in Japanese type 2 diabetic patients.

Diabetes care - 1 Apr 2006

Yamasaki Hiroshi, Sasaki Hideyuki, Ogawa Kenichi, Shono Takeshi, Tamura Shinobu, Doi Asako, Sasahara Miyoshi, Kawashima Hiromichi, Nakao Taisei, Furuta Hiroto, Nishi Masahiro, Nanjo Kishio

Abstract excerpt

OBJECTIVE: To determine genetic predispositions for diabetic polyneuropathy, we investigated the relationship between the -866G/A polymorphism of uncoupling protein (UCP) 2 and neurological manifestations in 197 type 2 diabetic patients. RESEARCH DESIGN AND METHODS: We first examined whether UCP2 mRNA had been expressed in the dorsal root ganglion (DRG) in four Long-Evans Tokushima Otsuka rats using RT-PCR and...

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Source

Identifiers

PMID: 16567833
DOI: 10.2337/diacare.29.04.06.dc05-1984

Genes

UCP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Uncoupling protein 2 promoter polymorphism -866G/A affects peripheral nerve dysfunction in Japanese type 2 diabetic patients.PMID 16567833Read ↗

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Mitochondrial uncoupling protein 2 (UCP2) gene polymorphism - 866 G/A in the promoter region is associated with type 2 diabetes mellitus among Kashmiri population of Northern India.Semantic proximity Read ↗

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Association study of the -866G/A UCP2 gene promoter polymorphism with type 2 diabetes and obesity in a Tehran population: a case control study.Semantic proximity Read ↗

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Uncoupling protein 2 promoter polymorphism -866G/A affects its expression in beta-cells and modulates clinical profiles of Japanese type 2 diabetic patients.Semantic proximity Read ↗

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