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Article

Uncoupling protein 2 G(-866)A polymorphism: a new gene polymorphism associated with C-reactive protein in type 2 diabetic patients.

Cardiovascular diabetology - 28 Oct 2010

Lapice Emanuela, Pinelli Michele, Pisu Elisabetta, Monticelli Antonella, Gambino Roberto, Pagano Gianfranco, Valsecchi Silvia, Cocozza Sergio, Riccardi Gabriele, Vaccaro Olga

Abstract excerpt

BACKGROUND: This study evaluated the relationship between the G(-866)A polymorphism of the uncoupling protein 2 (UCP2) gene and high-sensitivity C reactive protein (hs-CRP) plasma levels in diabetic patients. METHODS: We studied 383 unrelated people with type 2 diabetes aged 40-70 years. Anthropo...

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Source

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Identifiers

PMID: 21029457
DOI: 10.1186/1475-2840-9-68
PMCID: PMC2987999

Genes

CRP
UCP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21029457-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Uncoupling protein 2 G(-866)A polymorphism: a new gene polymorphism associated with C-reactive protein in type 2 diabetic patients.PMID 21029457Read ↗

Cardiovascular risk in healthy men and markers of oxidative stress in diabetic men are associated with common variation in the gene for uncoupling protein 2.Semantic proximity Read ↗

The frequent UCP2 -866G>A polymorphism protects against insulin resistance and is associated with obesity: a study of obesity and related metabolic traits among 17 636 Danes.Semantic proximity Read ↗

The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes.Semantic proximity Read ↗

Interaction between the uncoupling protein 2 -866G>A gene variant and cigarette smoking to increase oxidative stress in subjects with diabetes.Semantic proximity Read ↗

Mitochondrial uncoupling protein 2 (UCP2) gene polymorphism - 866 G/A in the promoter region is associated with type 2 diabetes mellitus among Kashmiri population of Northern India.Semantic proximity Read ↗

Mitochondrial uncoupling protein 2 (UCP2) gene polymorphism -866 G/A in the promoter region is associated with Type 2 Diabetes Mellitus among Kashmiri population of Northern IndiaSemantic proximity Read ↗

Association of uncoupling protein-2 -866G/A and Ala55Val polymorphisms with susceptibility to type 2 diabetes mellitus: A meta-analysis of case-control studies.Semantic proximity Read ↗

Association study of the -866G/A UCP2 gene promoter polymorphism with type 2 diabetes and obesity in a Tehran population: a case control study.Semantic proximity Read ↗

A common polymorphism in the promoter of UCP2 is associated with obesity and hyperinsulenemia in northern Indians.Semantic proximity Read ↗

Prevalence of uncoupling protein one genetic polymorphisms and their relationship with cardiovascular and metabolic healthSemantic proximity Read ↗

The common -866G/A polymorphism in the promoter region of the UCP-2 gene is associated with reduced risk of type 2 diabetes in Caucasians from Italy.Semantic proximity Read ↗

Interaction between the UCP2 -866 G>A polymorphism, diabetes, and beta-blocker use among patients with acute coronary syndromes.Semantic proximity Read ↗

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