Article
The development of artificial neural networks to predict virological response to combination HIV therapy.
Antiviral therapy - 1 Jan 2007
Larder Brendan, Wang Dechao, Revell Andrew, Montaner Julio, Harrigan Richard, De Wolf Frank, Lange Joep, Wegner Scott, Ruiz Lidia, Pérez-Elías Maria Jésus, Emery Sean, Gatell Jose, Monforte Antonella D'Arminio, Torti Carlo, Zazzi Maurizio, Lane Clifford
Abstract excerpt
INTRODUCTION: When used in combination, antiretroviral drugs are highly effective for suppressing HIV replication. Nevertheless, treatment failure commonly occurs and is generally associated with viral drug resistance. The choice of an alternative regimen may be guided by a drug-resistance test. However, interpretation of resistance from genotypic data poses a major challenge. METHODS: As an alternative to...
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