Article
Comparison of classifier fusion methods for predicting response to anti HIV-1 therapy.
PloS one - 1 Jan 2008
Altmann André, Rosen-Zvi Michal, Prosperi Mattia, Aharoni Ehud, Neuvirth Hani, Schülter Eugen, Büch Joachim, Struck Daniel, Peres Yardena, Incardona Francesca, Sönnerborg Anders, Kaiser Rolf, Zazzi Maurizio, Lengauer Thomas
Abstract excerpt
BACKGROUND: Analysis of the viral genome for drug resistance mutations is state-of-the-art for guiding treatment selection for human immunodeficiency virus type 1 (HIV-1)-infected patients. These mutations alter the structure of viral target proteins and reduce or in the worst case completely inhibit the effect of antiretroviral compounds while maintaining the ability for effective replication. Modern anti-HIV-1...
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