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Pretibial myxedema is associated with polymorphism in exon 1 of CTLA-4 gene in patients with Graves' ophthalmopathy.

Archives of dermatological research - 1 Oct 2009

Khalilzadeh Omid, Mojazi Amiri Hoda, Tahvildari Maryam, Anvari Mehdi, Esteghamati Alireza, Mobarra Zahra, Tehranchinia Zohreh, Rashidi Armin, Amirzargar Aliakbar

Abstract excerpt

Cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) is a well-known molecule that regulates T cell activity, with polymorphisms at different regions of this gene having been associated with autoimmune conditions. Pretibial myxedema (PTM), also called Graves' dermopathy, is an autoimmune extrathyroidal manifestation of Graves' disease. We opted to investigate the relationship between three single nucleotide...

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Identifiers

PMID: 19037649
DOI: 10.1007/s00403-008-0919-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Pretibial myxedema is associated with polymorphism in exon 1 of CTLA-4 gene in patients with Graves' ophthalmopathy.PMID 19037649Read ↗

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