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Article

Monoamine oxidase-A polymorphisms might modify the association between the dopamine D2 receptor gene and alcohol dependence.

Journal of psychiatry & neuroscience : JPN - 1 May 2007

Huang San-Yuan, Lin Wei-Wen, Wan Fang-Jung, Chang Ai-Ju, Ko Huei-Chen, Wang Tso-Jen, Wu Pei-Lin, Lu Ru-Band

Abstract excerpt

OBJECTIVE: Low monoamine oxidase (MAO) activity and the neurotransmitter dopamine are 2 important factors in the development of alcohol dependence. MAO is an important enzyme associated with the metabolism of biogenic amines. Therefore, the present study investigates whether the association between the dopamine D2 receptor (DRD2) gene and alcoholism is affected by different polymorphisms of the MAO type A (MAOA)...

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Source

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Identifiers

PMID: 17476365
PMCID: PMC1863553

Genes

DRD2
MAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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