Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic characteristics and proliferative activity of hyperplastic ductule cells in cholangiofibrosis induced by thioacetamide in rats.

Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie - 1 Mar 2013

Hata Masaki, Iida Hiroya, Yamanegi Koji, Yamada Naoko, Ohyama Hideki, Hirano Hiroshi, Nakasho Keiji, Terada Nobuyuki

Abstract excerpt

The oral administration of thioacetamide to rats induces cholangiofibrosis characterized by hyperplasia of ductules surrounded by fibrous tissue. In the present study, we examined the expression of markers of cholangiocyte and hepatocyte phenotypes in these hyperplastic ductule cells and their proliferative activity immunohistochemically. The oral administration of thioacetamide to 21-day-old male Fisher 344 rats...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bile Ducts
Share to Cell Proliferation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fibrosis

Share to Hepatocytes

Share to Hyperplasia

Share to Immunohistochemistry

Share to Liver Cirrhosis

Share to Rats, Inbred F344

Source

Identifiers

PMID: 22206608
DOI: 10.1016/j.etp.2011.11.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic characteristics and proliferative activity of hyperplastic ductule cells in cholangiofibrosis induced by thioacetamide in rats.PMID 22206608Read ↗

Phenotypic characterization of metaplastic intestinal glands and ductular hepatocytes in cholangiofibrotic lesions rapidly induced in the caudate liver lobe of rats treated with furan.Semantic proximity Read ↗

Expression of hepatocytic- and biliary-specific transcription factors in regenerating bile ducts during hepatocyte-to-biliary epithelial cell transdifferentiationSemantic proximity Read ↗

Induction of autophagy promotes the growth of early preneoplastic rat liver nodulesSemantic proximity Read ↗

Hepatobiliary pathology.Semantic proximity Read ↗

Anchoring hepatic gene expression with development of fibrosis and neoplasia in a toxicant-induced fish model of liver injury.Semantic proximity Read ↗

Fibrosis correlates with a ductular reaction in hepatitis C: roles of impaired replication, progenitor cells and steatosis.Semantic proximity Read ↗

Altered gene expression in <i>Opisthorchis viverrini</i>‐associated cholangiocarcinoma in hamster modelSemantic proximity Read ↗

Immunohistochemical Analysis of Cytokeratin 7 Expression in Resting and Proliferating Biliary Structures of Rat Liver *Semantic proximity Read ↗

Tissue culture correlational study of genetic cholangiopathy of autosomal recessive polycystic kidney disease.Semantic proximity Read ↗

Phenotype and differentiation patterns of the oval cell lines OC/CDE 6 and OC/CDE 22 derived from the livers of carcinogen-treated rats.Semantic proximity Read ↗

Pivotal roles of Kupffer cells in the progression and regression of DDC-induced chronic cholangiopathy.Semantic proximity Read ↗

Mallory body forming cells express the preneoplastic hepatocyte phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.