Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PERILIPIN-dependent control of lipid droplet structure and fat storage in Drosophila.

Cell metabolism - 3 Nov 2010

Beller Mathias, Bulankina Anna V, Hsiao He-Hsuan, Urlaub Henning, Jäckle Herbert, Kühnlein Ronald P

Abstract excerpt

Lipid droplets are intracellular organelles enriched in adipose tissue that govern the body fat stores of animals. In mammals, members of the evolutionarily conserved PERILIPIN protein family are associated with the lipid droplet surface and participate in lipid homeostasis. Here, we show that Drosophila mutants lacking the PERILIPIN PLIN1 are hyperphagic and suffer from adult-onset obesity. PLIN1 is a central...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila
Share to Drosophila Proteins
Share to Fats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipid Metabolism

Share to Mutation

Share to Obesity

Source

Identifiers

PMID: 21035762
DOI: 10.1016/j.cmet.2010.10.001

Genes

PLIN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PERILIPIN-dependent control of lipid droplet structure and fat storage in Drosophila.PMID 21035762Read ↗

Drosophila Perilipin/ADRP homologue Lsd2 regulates lipid metabolism.Semantic proximity Read ↗

Perilipin Deficiency and Autosomal Dominant Partial LipodystrophySemantic proximity Read ↗

COPI complex is a regulator of lipid homeostasis.Semantic proximity Read ↗

Drosophila Lipid Storage Droplet 2 gene (Lsd-2) is expressed and controls lipid storage in wing imaginal discs.Semantic proximity Read ↗

Perilipin-related protein regulates lipid metabolism in <i>C. elegans</i>Semantic proximity Read ↗

Function of Lipid Storage Droplet 1 (Lsd1) in Wing Development of Drosophila melanogaster.Semantic proximity Read ↗

The Drosophila model to interrogate triacylglycerol biologySemantic proximity Read ↗

Functional genomic screen reveals genes involved in lipid-droplet formation and utilization.Semantic proximity Read ↗

Clinical and Molecular Characterization of a Novel PLIN1 Frameshift Mutation Identified in Patients With Familial Partial LipodystrophySemantic proximity Read ↗

Perilipin 1: a systematic review on its functions on lipid metabolism and atherosclerosis in mice and humans.Semantic proximity Read ↗

Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formation.Semantic proximity Read ↗

Comparative study of Dog and Human Lipid Droplet-associated protein (PLIN2)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.