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Article

Shedding of vaccine viruses with increased antigenic and genetic divergence after vaccination of newborns with monovalent type 1 oral poliovirus vaccine.

Journal of virology - 1 Sept 2009

van der Sanden Sabine, Pallansch Mark A, van de Kassteele Jan, El-Sayed Nasr, Sutter Roland W, Koopmans Marion, van der Avoort Harrie

Abstract excerpt

For the final stages in the eradication of poliovirus type 1 (P1), the World Health Organization advocates the selective use of monovalent type 1 oral poliovirus vaccine (mOPV1). To compare the immunogenicity of mOPV1 with that of trivalent OPV (tOPV) in infants, a study was performed in Egypt in 2005. Newborns were vaccinated with mOPV1 or tOPV immediately after birth and were challenged with mOPV1 after 1...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 19515771
DOI: 10.1128/JVI.02388-08
PMCID: PMC2738206

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Source receipt: pubmed, retrieved 7 Sept 2026.

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