Article
Genetic associations of variants of the high affinity receptor for immunoglobulin E in Wegener's granulomatosis.
Polskie Archiwum Medycyny Wewnetrznej - 1 Mar 2009
Sanak Marek, Potaczek Daniel P, Sznajd Jan, Musiał Jacek, Szczeklik Andrzej
Abstract excerpt
Immunoglobulin E (IgE) and the high affinity IgE receptor (FcepsilonRI) have been suggested to contribute to the pathogenesis of autoimmune disorders. Their role in Wegener's granulomatosis (WG) are, however, poorly recognized. We sought a genetic association between laboratory markers for the disease, i.e. anti-proteinase 3 antibodies (anti-PR3), anti-myeloperoxidase antibodies, anti-cyclic citrullinated peptide...
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