Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dissecting the fibrillin microfibril: structural insights into organization and function.

Structure (London, England : 1993) - 8 Feb 2012

Jensen Sacha A, Robertson Ian B, Handford Penny A

Abstract excerpt

Force-bearing tissues such as blood vessels, lungs, and ligaments depend on the properties of elasticity and flexibility. The 10 to 12 nm diameter fibrillin microfibrils play vital roles in maintaining the structural integrity of these highly dynamic tissues and in regulating extracellular growth factors. In humans, defective microfibril function results in several diseases affecting the skin, cardiovascular,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Motifs
Share to Calcium
Share to Elasticity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fibrillin-1

Share to Fibrillins

Share to Microfibrils

Share to Microfilament Proteins

Share to Protein Structure, Quaternary

Source

Identifiers

PMID: 22325771
DOI: 10.1016/j.str.2011.12.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dissecting the fibrillin microfibril: structural insights into organization and function.PMID 22325771Read ↗

New insights into the structure, assembly and biological roles of 10-12 nm connective tissue microfibrils from fibrillin-1 studies.Semantic proximity Read ↗

Fibrillin microfibrils: connective tissue pathways that regulate shape and signaling.Semantic proximity Read ↗

Fibrillin: monomers and microfibrils.Semantic proximity Read ↗

Structural and functional failure of fibrillin‑1 in human diseases (Review)Semantic proximity Read ↗

Biogenesis and function of fibrillin assemblies.Semantic proximity Read ↗

The Multiple Functions of Fibrillin-1 Microfibrils in Organismal Physiology.Semantic proximity Read ↗

Fibrillin assemblies: extracellular determinants of tissue formation and fibrosisSemantic proximity Read ↗

Fibrillin-containing microfibrils: structure and function in health and disease.Semantic proximity Read ↗

Fibrillin‐rich microfibrils: Structural determinants of morphogenetic and homeostatic eventsSemantic proximity Read ↗

The fibrillin-Marfan syndrome connection.Semantic proximity Read ↗

The fibrillin microfibril scaffold: A niche for growth factors and mechanosensation?Semantic proximity Read ↗

Fibrillin microfibril structure identifies long-range effects of inherited pathogenic mutations affecting a key regulatory TGFβ-binding siteSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.