Overexpression of human MX2 gene suppresses cell proliferation, migration, and invasion via ERK/P38/NF‐κB pathway in glioblastoma cells

Abstract excerpt

In human, there are two myxovirus resistance genes-MX1 and MX2, which respectively encode MXA and MXB protein. For MXB, it was traditionally deemed to work in the progression of cell cycle and adjustment of nuclear import. Thus, we speculated that it might play important roles in tumor progression. The purpose of this study was to preliminarily explore the underlying functions and mechanism of the MX2 gene on...

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