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Article

Gene conversion transfers the GAF-A domain of phosphodiesterase TbrPDEB1 to one allele of TbrPDEB2 of Trypanosoma brucei.

PLoS neglected tropical diseases - 9 Jun 2009

Kunz Stefan, Luginbuehl Edith, Seebeck Thomas

Abstract excerpt

BACKGROUND: Chromosome 9 of Trypanosoma brucei contains two closely spaced, very similar open reading frames for cyclic nucleotide specific phosphodiesterases TbrPDEB1 and TbrPDEB2. They are separated by 2379 bp, and both code for phosphodiesterases with two GAF domains in their N-terminal moieties and a catalytic domain at the C-terminus. METHODS AND FINDINGS: The current study reveals that in the Lister427...

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Identifiers

PMID: 19513125
DOI: 10.1371/journal.pntd.0000455
PMCID: PMC2689650

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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