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Article

Tandem duplication of rab genes followed by sequence divergence and acquisition of distinct functions in Trypanosoma brucei.

The Journal of biological chemistry - 18 Apr 1997

Field H, Field M C

Abstract excerpt

The Ras superfamily of small G proteins governs unidirectional cellular processes by virtue of GTP hydrolysis and concomitant conformational changes, which are in turn regulated by a number of accessory factors. Members of the Rab subfamily are important for correct targeting and fusion of intra-organellar vesicles loaded with trafficking proteins and lipids. During evolution from a prototype gene, novel...

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PMID: 9099693
DOI: 10.1074/jbc.272.16.10498

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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