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The ever unfolding story of cAMP signaling in trypanosomatids: vive la difference!

7 Sept 2015

Abstract excerpt

Kinetoplastids are unicellular, eukaryotic, flagellated protozoans containing the eponymous kinetoplast. Within this order, the family of trypanosomatids are responsible for some of the most serious human diseases, including Chagas disease (Trypanosoma cruzi), sleeping sickness (Trypanosoma brucei spp.), and leishmaniasis (Leishmania spp). Although cAMP is produced during the life cycle stages of these parasites,...

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PMID: 26441645
DOI: 10.3389/fphar.2015.00185

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