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Article

Selective inhibition of PGE2 production in cells transfected with c-fms encoded CSF-1 receptor genes by the tyrosine kinase inhibitor, ST638.

Agents and actions - 1 Jul 1991

Puri J, Pierce J H, Hoffman T

Abstract excerpt

In this study, we investigated the effect of ST638, a novel tyrosine kinase inhibitor, on TPA and ionomycin-stimulated PGE2 production after transfection of c-fms encoded CSF-1 receptor (CSF-1R) DNA (with or without transforming activity) into the myeloid progenitor cell line, 32D. ST638 inhibite...

Topics

Arachidonic Acid
Cells, Cultured
Cinnamates
Dinoprostone
Humans
Indicators and Reagents
Interleukin-3
Ionomycin
Phenotype
Protein-Tyrosine Kinases
Receptors, Colony-Stimulating Factor
Sulfides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tetradecanoylphorbol Acetate

Transfection

Source

Identifiers

PMID: 1950818
DOI: 10.1007/BF01986579

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1950818-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Selective inhibition of PGE2 production in cells transfected with c-fms encoded CSF-1 receptor genes by the tyrosine kinase inhibitor, ST638.PMID 1950818Read ↗

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