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Article

Strategy to control type I error increases power to identify genetic variation using the full biological trajectory.

Genetic epidemiology - 1 Jul 2013

Benke K S, Wu Y, Fallin D M, Maher B, Palmer L J

Abstract excerpt

Genome-wide association studies have been successful in identifying loci that underlie continuous traits measured at a single time point. To additionally consider continuous traits longitudinally, it is desirable to look at SNP effects at baseline and over time using linear-mixed effects models. Estimation and interpretation of two coefficients in the same model raises concern regarding the optimal control of...

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PMID: 23633177
DOI: 10.1002/gepi.21733
PMCID: PMC3877575

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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