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Article

Optimizing the power of genome-wide association studies by using publicly available reference samples to expand the control group.

Genetic epidemiology - 1 May 2010

Zhuang Joanna J, Zondervan Krina, Nyberg Fredrik, Harbron Chris, Jawaid Ansar, Cardon Lon R, Barratt Bryan J, Morris Andrew P

Abstract excerpt

Genome-wide association (GWA) studies have proved extremely successful in identifying novel genetic loci contributing effects to complex human diseases. In doing so, they have highlighted the fact that many potential loci of modest effect remain undetected, partly due to the need for samples cons...

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Identifiers

PMID: 20088020
DOI: 10.1002/gepi.20482
PMCID: PMC2962805

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20088020-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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