Article
Acetic acid induces expression of the Staphylococcus aureus cidABC and lrgAB murein hydrolase regulator operons.
Journal of bacteriology - 1 Feb 2005
Rice Kelly C, Nelson Jeremy B, Patton Toni G, Yang Soo-Jin, Bayles Kenneth W
Abstract excerpt
The Staphylococcus aureus lrg and cid operons encode homologous proteins that regulate extracellular murein hydrolase activity and penicillin tolerance in a diametrically opposing manner. Although their specific regulatory functions remain unknown, it has been postulated that the functions of CidA and LrgA are analogous to those of bacteriophage holins and antiholins, respectively, and that these proteins serve...
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