Article
The Staphylococcus aureus lrgAB operon modulates murein hydrolase activity and penicillin tolerance.
Journal of bacteriology - 1 Apr 2000
Groicher K H, Firek B A, Fujimoto D F, Bayles K W
Abstract excerpt
Previous studies in our laboratory have shown that the Staphylococcus aureus LytSR two-component regulatory system affects murein hydrolase activity and autolysis. A LytSR-regulated dicistronic operon has also been identified and shown to encode two potential membrane-associated proteins, designated LrgA and LrgB, hypothesized to be involved in the control of murein hydrolase activity. In the present study, a...
Topics
- Amino Acid Sequence
- Bacterial Proteins
- Bacteriolysis
- Gene Deletion
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Genes, Regulator
- Genetic Complementation Test
- Membrane Proteins
- Microbial Sensitivity Tests
- Molecular Sequence Data
- N-Acetylmuramoyl-L-alanine Amidase
- Operon