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Article

Contribution of the Staphylococcus aureus Atl AM and GL murein hydrolase activities in cell division, autolysis, and biofilm formation.

PloS one - 1 Jan 2012

Bose Jeffrey L, Lehman McKenzie K, Fey Paul D, Bayles Kenneth W

Abstract excerpt

The most prominent murein hydrolase of Staphylococcus aureus, AtlA, is a bifunctional enzyme that undergoes proteolytic cleavage to yield two catalytically active proteins, an amidase (AM) and a glucosaminidase (GL). Although the bifunctional nature of AtlA has long been recognized, most studies have focused on the combined functions of this protein in cell wall metabolism and biofilm development. In this study,...

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Identifiers

PMID: 22860095
DOI: 10.1371/journal.pone.0042244
PMCID: PMC3409170

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