Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Staphylococcus aureus cidAB operon: evaluation of its role in regulation of murein hydrolase activity and penicillin tolerance.

Journal of bacteriology - 1 Apr 2003

Rice Kelly C, Firek Brian A, Nelson Jeremy B, Yang Soo-Jin, Patton Toni G, Bayles Kenneth W

Abstract excerpt

Recent studies have shown that expression of the Staphylococcus aureus lrgAB operon inhibits murein hydrolase activity and decreases sensitivity to penicillin-induced killing. It was proposed that the lrgAB gene products function in a manner analogous to an antiholin, inhibiting a putative holin from transporting murein hydrolases out of the cell. In the present study the cidAB operon was identified and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Proteins

Share to Microbial Sensitivity Tests

Share to N-Acetylmuramoyl-L-alanine Amidase

Share to Operon

Share to Penicillin Resistance

Share to Staphylococcus aureus

Source

Open in PubMed Open full text

Identifiers

PMID: 12670989
DOI: 10.1128/JB.185.8.2635-2643.2003
PMCID: PMC152627

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Staphylococcus aureus cidAB operon: evaluation of its role in regulation of murein hydrolase activity and penicillin tolerance.PMID 12670989Read ↗

Acetic acid induces expression of the Staphylococcus aureus cidABC and lrgAB murein hydrolase regulator operons.Semantic proximity Read ↗

Characterization of the Staphylococcus aureus CidR regulon: elucidation of a novel role for acetoin metabolism in cell death and lysis.Semantic proximity Read ↗

The Staphylococcus aureus lrgAB operon modulates murein hydrolase activity and penicillin tolerance.Semantic proximity Read ↗

The Staphylococcus aureus LytSR two-component regulatory system affects biofilm formation.Semantic proximity Read ↗

The bactericidal action of penicillin: new clues to an unsolved mystery.Semantic proximity Read ↗

Characterization of CidR-mediated regulation in Bacillus anthracis reveals a previously undetected role of S-layer proteins as murein hydrolases.Semantic proximity Read ↗

Understanding the Streptococcus mutans Cid/Lrg System through CidB FunctionSemantic proximity Read ↗

Transcriptional profiling of the clpX mutant in Bacillus anthracis reveals regulatory connection with the lrgAB operon.Semantic proximity Read ↗

The CodY-dependent clhAB2 operon is involved in cell shape, chaining and autolysis in Bacillus cereus ATCC 14579.Semantic proximity Read ↗

The Streptococcus mutans Cid and Lrg systems modulate virulence traits in response to multiple environmental signals.Semantic proximity Read ↗

A potential space-making role in cell wall biogenesis for SltB1and DacB revealed by a beta-lactamase induction phenotype in Pseudomonas aeruginosa.Semantic proximity Read ↗

Characterization of mutants deficient in the L,D-carboxypeptidase (DacB) and WalRK (VicRK) regulon, involved in peptidoglycan maturation of Streptococcus pneumoniae serotype 2 strain D39.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.