Article
SaeRS Is Responsive to Cellular Respiratory Status and Regulates Fermentative Biofilm Formation in Staphylococcus aureus.
Infection and immunity - 1 Aug 2017
Mashruwala Ameya A, Gries Casey M, Scherr Tyler D, Kielian Tammy, Boyd Jeffrey M
Abstract excerpt
Biofilms are multicellular communities of microorganisms living as a quorum rather than as individual cells. The bacterial human pathogen Staphylococcus aureus uses oxygen as a terminal electron acceptor during respiration. Infected human tissues are hypoxic or anoxic. We recently reported that impaired respiration elicits a programmed cell lysis (PCL) phenomenon in S. aureus leading to the release of cellular...
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