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Article

The Streptococcus mutans Cid and Lrg systems modulate virulence traits in response to multiple environmental signals.

Microbiology (Reading, England) - 1 Oct 2010

Ahn Sang-Joon, Rice Kelly C, Oleas Janneth, Bayles Kenneth W, Burne Robert A

Abstract excerpt

The tight control of autolysis by Streptococcus mutans is critical for proper virulence gene expression and biofilm formation. A pair of dicistronic operons, SMU.575/574 (lrgAB) and SMU.1701/1700 (designated cidAB), encode putative membrane proteins that share structural features with the bacteriophage-encoded holin family of proteins, which modulate host cell lysis during lytic infection. Analysis of S. mutans...

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Identifiers

PMID: 20671018
DOI: 10.1099/mic.0.039586-0
PMCID: PMC3068699

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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