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Article

Polymorphisms in NF-kappaB inhibitors and risk of epithelial ovarian cancer.

BMC cancer - 6 Jun 2009

White Kristin L, Vierkant Robert A, Phelan Catherine M, Fridley Brooke L, Anderson Stephanie, Knutson Keith L, Schildkraut Joellen M, Cunningham Julie M, Kelemen Linda E, Pankratz V Shane, Rider David N, Liebow Mark, Hartmann Lynn C, Sellers Thomas A, Goode Ellen L

Abstract excerpt

BACKGROUND: The nuclear factor-kappaB (NF-kappaB) family is a set of transcription factors with key roles in the induction of the inflammatory response and may be the link between inflammation and cancer development. This pathway has been shown to influence ovarian epithelial tissue repair. Inhibitors of kappaB (IkappaB) prevent NF-kappaB activation by sequestering NF-kappaB proteins in the cytoplasm until...

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Identifiers

PMID: 19500386
DOI: 10.1186/1471-2407-9-170
PMCID: PMC2706256

Genes

NFKBIA
NFKBIB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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