Article
NFKB and NFKBI polymorphisms in relation to susceptibility of tumour and other diseases.
Histology and histopathology - 1 Dec 2007
Sun X-F, Zhang H
Abstract excerpt
Nuclear factor-kappaB (NF-kappaB) is responsible for the expression by regulating many genes for immune response, cell adhesion, differentiation, proliferation, angiogenesis and apoptosis. The function of NF-kappaB is inhibited by binding to NF-kappaB inhibitor (IkappaB), and imbalance of NF-kappaB and IkappaB has been associated with development of many diseases, including tumours. In this review, we focus on...
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