Article
Polymorphisms in the IkappaB-alpha promoter region and risk of diseases involving inflammation and fibrosis.
Genes and immunity - 1 May 2001
Mozzato-Chamay N, Corbett E L, Bailey R L, Mabey D C, Raynes J, Conway D J
Abstract excerpt
The transcription factor NFkappaB regulates inflammatory and other cellular responses. In non-stimulated cells, NFkappaB is linked to its inhibitor IkappaB, which plays a major role in controlling NFkappaB activity. Here, the gene promoter region of the major inducible IkappaB component (IkappaB-...
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