Article
Confirmation of quantitative trait loci for ethanol sensitivity and neurotensin receptor density in crosses derived from the inbred high and low alcohol sensitive selectively bred rat lines.
Psychopharmacology - 1 Oct 2006
Radcliffe Richard A, Bludeau Pequita, Asperi William, Fay Tina, Deng X-S, Erwin V Gene, Deitrich Richard A
Abstract excerpt
RATIONALE: Genetically influenced alcohol sensitivity is thought to be an important risk factor for the development of alcoholism. An effective first step for identifying genes that mediate variation in alcohol sensitivity is through quantitative trait loci (QTL) mapping in model organisms. OBJECTIVE: Fourteen provisional QTLs related to alcohol sensitivity were previously mapped in an F2 derived from the IHAS1...
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