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Article

Detection of novel NF2 mutations by an RNA mismatch cleavage method.

Human mutation - 1 Jan 2000

Faudoa R, Xue Z, Lee F, Baser M E, Hung G

Abstract excerpt

Mutations in the neurofibromatosis type 2 gene (NF2) cause benign nervous system tumors. Common methods for detecting NF2 mutations (such as single stranded conformational polymorphism analysis and denaturing gradient gel electrophoresis) are laborious and time-consuming. We adapted and improved a commercial assay, the Non-Isotopic RNase Cleavage Assay (NIRCAtrade mark, Ambion, Austin, TX) for rapid,...

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Source

Identifiers

PMID: 10790209
DOI: 10.1002/(SICI)1098-1004(200005)15:5<474::AID-HUMU9>3.0.CO;2-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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