Article
Genetic variation in schizophrenia-risk-gene dysbindin 1 modulates brain activation in anterior cingulate cortex and right temporal gyrus during language production in healthy individuals.
NeuroImage - 1 Oct 2009
Markov V, Krug A, Krach S, Whitney C, Eggermann T, Zerres K, Stöcker T, Shah N J, Nöthen M M, Treutlein J, Rietschel M, Kircher T
Abstract excerpt
Genetic variation in dysbindin 1 (DTNBP1) gene region tagged by SNP rs1018381 exhibits a linkage with cognitive deficits in patients with schizophrenia and healthy subjects. Language production deficits are core features of schizophrenia with more impairment in semantic than lexical verbal fluency tasks. We investigated the link between brain activation and DTNBP1 SNP rs1018381 during semantic verbal fluency task...
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