Article
DTNBP1 (dysbindin) gene variants modulate prefrontal brain function in healthy individuals.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Sept 2006
Fallgatter Andreas J, Herrmann Martin J, Hohoff Christa, Ehlis Ann-Christine, Jarczok Tomasz A, Freitag Christine M, Deckert Jürgen
Abstract excerpt
DTNBP1 (dysbindin) is one of the several putative schizophrenia genes supported by association, neuroanatomical, and cellular studies. These suggest an involvement of DTNBP1 in the prefrontal cortex and cognitive functions mediated by interaction with neurotransmitter systems, in particular glutamate. The influence of DTNBP1 gene variation on prefrontal brain function at the systemic neurophysiological level,...
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