Article
Fatty acid desaturation and the regulation of adiposity in Caenorhabditis elegans.
Genetics - 1 Jun 2007
Brock Trisha J, Browse John, Watts Jennifer L
Abstract excerpt
Monounsaturated fatty acids are essential components of membrane and storage lipids. Their synthesis depends on the conversion of saturated fatty acids to unsaturated fatty acids by Delta9 desaturases. Caenorhabditis elegans has three Delta9 desaturases encoded by the genes fat-5, fat-6, and fat-7. We generated nematodes that display a range of altered fatty acid compositions by constructing double-mutant strains...
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