Article
Familiality of novel factorial dimensions of schizophrenia.
Archives of general psychiatry - 1 Jun 2009
McGrath John A, Avramopoulos Dimitrios, Lasseter Virginia K, Wolyniec Paula S, Fallin M Daniele, Liang Kung-Yee, Nestadt Gerald, Thornquist Mary H, Luke James R, Chen Pei-Lung, Valle David, Pulver Ann E
Abstract excerpt
CONTEXT: Factor analysis of the signs and symptoms of schizophrenia yields dimensional phenotypes that may relate to underlying genetic variation. Examination of familiality of factor scores can demonstrate whether they are likely to be of use in genetic research. OBJECTIVE: To produce a broader set of factorial phenotypes that are tested for familiality including core symptoms of schizophrenia and additional...
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