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Article

Finding suitable phenotypes for genetic studies of schizophrenia: heritability and segregation analysis.

Biological psychiatry - 15 Jul 2008

Aukes Maartje F, Alizadeh Behrooz Z, Sitskoorn Margriet M, Selten Jean-Paul, Sinke Richard J, Kemner Chantal, Ophoff Roel A, Kahn René S

Abstract excerpt

BACKGROUND: Schizophrenia is a highly heritable and complex disorder. Multiple genes are likely to be involved, complicating genetic research into the etiology of this disorder. Intermediate phenotypes or endophenotypes may facilitate genetic research if they display a simpler mode of transmission than schizophrenia itself, i.e., if they reflect more closely the underlying genetic effects. METHODS: Twenty-five...

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Identifiers

PMID: 18295748
DOI: 10.1016/j.biopsych.2007.12.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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